Fractyl Health, Inc. Common Stock

Fractyl Health, Inc. Common Stockverified

GUTS

Price:

$1.98

Market Cap:

$142.94M

Fractyl Health, Inc., a metabolic therapeutics company, develops therapies for the treatment of type 2 diabetes (T2D) and obesity. The company develops Revita DMR System (Revita), an outpatient procedural therapy designed to durably modify duodenal dysfunction, a pathologic consequence of a high fat and high sugar diet, which can initiate T2D and obesity in humans. It also develops Rejuva, a novel virus delivered pancreatic gene therapy platform that is designed to enable long-term remission of T2D and obesity by durably altering metabolic hormone function in the pancreatic islet cells of patients. Fractyl Health, Inc. was formerly known as Fractyl Laboratories Inc. and changed its name to F...[Read more]

Industry

Biotechnology

IPO Date

2024-02-02

Stock Exchange

NASDAQ

Ticker

GUTS

The PE Ratio as of December 2025 (TTM) for Fractyl Health, Inc. Common Stock (GUTS) is -0.85

According to Fractyl Health, Inc. Common Stock’s latest financial reports and current stock price. The company's current PE Ratio is -0.85. This represents a change of 17.49% compared to the average of -0.72 of the last 4 quarters.

Fractyl Health, Inc. Common Stock (GUTS) Historical PE Ratio (quarterly & annually)

How has GUTS PE Ratio performed in the past?

The mean historical PE Ratio of Fractyl Health, Inc. Common Stock over the last ten years is -13.05. The current -0.85 PE Ratio has changed 551.58% with respect to the historical average. Over the past ten years (40 quarters), GUTS's PE Ratio was at its highest in in the September 2025 quarter at -0.56. The PE Ratio was at its lowest in in the March 2024 quarter at -26.85.

Quarterly (TTM)
Annual

Average

-13.05

Median

-14.48

Minimum

-20.07

Maximum

-1.31

Fractyl Health, Inc. Common Stock (GUTS) PE Ratio by Quarter and Year

Discovering the peaks and valleys of Fractyl Health, Inc. Common Stock PE Ratio, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 0.37%

Maximum Annual PE Ratio = -1.31

Minimum Annual Increase = -83.55%

Minimum Annual PE Ratio = -20.07

Quarterly (TTM)
Annual
YearPE RatioChange
2024-1.31-83.55%
2023-7.94-39.74%
2022-13.17-16.61%
2021-15.79-21.31%
2020-20.070.37%

Fractyl Health, Inc. Common Stock (GUTS) Average PE Ratio

How has GUTS PE Ratio performed in the past?

The current PE Ratio of Fractyl Health, Inc. Common Stock (GUTS) is greater than its 3-year, greater than its 5-year, and greater than its 10-year historical averages

3-year avg

-7.47

5-year avg

-11.65

10-year avg

-13.05

Fractyl Health, Inc. Common Stock (GUTS) PE Ratio vs. Peers

How is GUTS’s PE Ratio compared to its peers?

Fractyl Health, Inc. Common Stock’s PE Ratio is less than Adverum Biotechnologies, Inc. (-0.48), less than ALX Oncology Holdings Inc. (-0.63), less than Precision BioSciences, Inc. (-0.71), greater than Artiva Biotherapeutics, Inc. (-1.28), less than Sutro Biopharma, Inc. (-0.37), greater than Quince Therapeutics, Inc. (-3.43), less than Metagenomi, Inc. Common Stock (-0.76), greater than Repare Therapeutics Inc. (-1.33), greater than aTyr Pharma, Inc. (-1.07), greater than Biomea Fusion, Inc. (-0.90),

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