CalciMedica, Inc.

CalciMedica, Inc.verified

CALC

Price:

$4.57

Market Cap:

$65.85M

CalciMedica, Inc., a clinical-stage biotechnology company, focuses on developing therapies for life-threatening inflammatory diseases with unmet needs. Its proprietary technology targets the inhibition of calcium release-activated (CRAC) channels designs to modulate the immune response and protect against tissue cell injury in life-threatening inflammatory diseases. Its lead product candidate is Auxora, a proprietary intravenous-formulated CRAC channel inhibitor for the treatment of acute pancreatitis, asparaginase-associated acute pancreatitis, and acute kidney injury. The company is based in La Jolla, California.

Industry

Biotechnology

IPO Date

2023-06-14

Stock Exchange

NASDAQ

Ticker

CALC

The PE Ratio as of December 2025 (TTM) for CalciMedica, Inc. (CALC) is -2.82

According to CalciMedica, Inc.’s latest financial reports and current stock price. The company's current PE Ratio is -2.82. This represents a change of -99.24% compared to the average of -373.14 of the last 4 quarters.

CalciMedica, Inc. (CALC) Historical PE Ratio (quarterly & annually)

How has CALC PE Ratio performed in the past?

The mean historical PE Ratio of CalciMedica, Inc. over the last ten years is -0.60. The current -2.82 PE Ratio has changed 46.70% with respect to the historical average. Over the past ten years (40 quarters), CALC's PE Ratio was at its highest in in the March 2024 quarter at 73.72. The PE Ratio was at its lowest in in the September 2025 quarter at -1487.55.

Quarterly (TTM)
Annual

Average

-0.60

Median

-0.25

Minimum

-2.91

Maximum

-0.10

CalciMedica, Inc. (CALC) PE Ratio by Quarter and Year

Discovering the peaks and valleys of CalciMedica, Inc. PE Ratio, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 677.46%

Maximum Annual PE Ratio = -0.10

Minimum Annual Increase = -38.44%

Minimum Annual PE Ratio = -2.91

Quarterly (TTM)
Annual
YearPE RatioChange
2024-2.91677.46%
2023-0.3748.46%
2022-0.251.98%
2021-0.25146.18%
2020-0.10-38.44%
2019-0.16-7.67%

CalciMedica, Inc. (CALC) Average PE Ratio

How has CALC PE Ratio performed in the past?

The current PE Ratio of CalciMedica, Inc. (CALC) is less than than its 3-year, less than than its 5-year, and less than than its 10-year historical averages

3-year avg

-1.18

5-year avg

-0.78

10-year avg

-0.60

CalciMedica, Inc. (CALC) PE Ratio vs. Peers

How is CALC’s PE Ratio compared to its peers?

CalciMedica, Inc.’s PE Ratio is less than Tvardi Therapeutics, Inc. (-2.81), less than Lantern Pharma Inc. (-2.11), less than LAVA Therapeutics N.V. (-1.65), less than Actinium Pharmaceuticals, Inc. (-1.31), less than Elutia Inc. (-1.07), less than Reviva Pharmaceuticals Holdings, Inc. (-1.09), less than Xilio Therapeutics, Inc. (-2.53), less than PDS Biotechnology Corporation (-1.20), less than MAIA Biotechnology, Inc. (-2.25), greater than RenovoRx, Inc. (-3.26),

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