CalciMedica, Inc.

CalciMedica, Inc.verified

CALC

Price:

$0.867

Market Cap:

$13.70M

CalciMedica, Inc., a clinical-stage biotechnology company headquartered in La Jolla, California, is focused on creating treatments for life-threatening inflammatory diseases that currently lack adequate therapies. The company's proprietary approach involves blocking calcium release-activated (CRAC) channels, a mechanism designed to modulate the immune system and protect against cellular and tissue damage in these severe conditions. Their primary experimental drug, Auxora, is an intravenously administered, proprietary CRAC channel inhibitor being developed for the treatment of acute pancreatitis, including its asparaginase-associated form, and acute kidney injury.

Industry

Biotechnology

IPO Date

2023-06-14

Stock Exchange

NASDAQ

Ticker

CALC

The ROE as of June 2026 (TTM) for CalciMedica, Inc. (CALC) is 4.09%

According to CalciMedica, Inc.’s latest financial reports and current stock price. The company's current ROE is 4.09%. This represents a change of 548.23% compared to the average of 631.41% of the last 4 quarters.

CalciMedica, Inc. (CALC) Historical ROE (quarterly & annually)

How has CALC ROE performed in the past?

The mean historical ROE of CalciMedica, Inc. over the last ten years is -54.63%. The current 4.09% ROE has changed -7592.85% with respect to the historical average. Over the past ten years (40 quarters), CALC's ROE was at its highest in in the September 2025 quarter at 2.91%. The ROE was at its lowest in in the March 2026 quarter at -450.72%.

Quarterly (TTM)
Annual

Average

-54.63%

Median

-75.08%

Minimum

-421.20%

Maximum

445.14%

CalciMedica, Inc. (CALC) ROE by Quarter and Year

Discovering the peaks and valleys of CalciMedica, Inc. ROE, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 89.67%

Maximum Annual ROE = 445.14%

Minimum Annual Increase = -597.05%

Minimum Annual ROE = -421.20%

Quarterly (TTM)
Annual
YearROEChange
2025445.14%-568.21%
2024-95.07%-77.43%
2023-421.20%-597.05%
202284.74%-253.82%
2021-55.09%89.67%
2020-29.05%-77.72%
2019-130.37%-44.78%

CalciMedica, Inc. (CALC) Average ROE

How has CALC ROE performed in the past?

The current ROE of CalciMedica, Inc. (CALC) is greater than its 3-year, greater than its 5-year, and greater than its 10-year historical averages

3-year avg

-23.71%

5-year avg

-8.30%

10-year avg

-54.63%

CalciMedica, Inc. (CALC) ROE vs. Peers

How is CALC’s ROE compared to its peers?

CalciMedica, Inc.’s ROE is greater than Tvardi Therapeutics, Inc. (-64.17%), greater than Lantern Pharma Inc. (-0.97%), greater than LAVA Therapeutics N.V. (-108.07%), greater than Actinium Pharmaceuticals, Inc. (-218.67%), greater than Elutia Inc. (-560.64%), greater than Reviva Pharmaceuticals Holdings, Inc. (-220.39%), greater than Xilio Therapeutics, Inc. (-117.24%), greater than PDS Biotechnology Corporation (-346.03%), greater than MAIA Biotechnology, Inc. (-284.80%), greater than RenovoRx, Inc. (-138.61%),

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