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NASDAQ · SEPNBiotechnologyUpdated Nov 2, 2026

Septerna Inc enterprise value

Company valuation, historical trends, and peer comparisons.

The Enterprise Value as of November 2026 (TTM) for Septerna Inc (SEPN) is 1.93B

According to Septerna Inc’s latest financial reports and current stock price. The company's current Enterprise Value is 1.93B. This represents a change of 86.10% compared to the average of 1.04B of the last 4 quarters.

Septerna Inc (SEPN) Historical Enterprise Value (quarterly & annually)

How has SEPN Enterprise Value performed in the past?

The mean historical Enterprise Value of Septerna Inc over the last ten years is 521.81M. The current 1.93B Enterprise Value has changed 269.88% with respect to the historical average. Over the past ten years (40 quarters), SEPN's Enterprise Value was at its highest in in the June 2026 quarter at 1.45B. The Enterprise Value was at its lowest in in the September 2023 quarter at 0.

Quarterly (TTM)
Annual

Average

521.81M

Median

490.15M

Minimum

-29897000.00

Maximum

1.14B

Septerna Inc (SEPN) Enterprise Value by Quarter and Year

Discovering the peaks and valleys of Septerna Inc Enterprise Value, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 87.23%

Maximum Annual Enterprise Value = 1.14B

Minimum Annual Increase = -1241.56%

Minimum Annual Enterprise Value = -29897000.00

Quarterly (TTM)
Annual
YearEnterprise ValueChange
20251.14B77.91%
2024639.00M87.23%
2023341.29M-1241.56%

Septerna Inc (SEPN) Average Enterprise Value

How has SEPN Enterprise Value performed in the past?

The current Enterprise Value of Septerna Inc (SEPN) is greater than its 3-year, greater than its 5-year, and greater than its 10-year historical averages

3-year avg

705.71M

5-year avg

521.81M

10-year avg

521.81M

Septerna Inc (SEPN) Enterprise Value vs. Peers

How is SEPN’s Enterprise Value compared to its peers?

Septerna Inc’s Enterprise Value is greater than Structure Therapeutics Inc. (931.84M), greater than Maze Therapeutics, Inc. (1.55B), greater than Biomea Fusion, Inc. (11.96M), greater than Kailera Therapeutics, Inc. (1.47B), less than MBX Biosciences, Inc. Common Stock (2.59B), greater than vTv Therapeutics Inc. (8.70M),

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