Palvella Therapeutics, Inc.

Palvella Therapeutics, Inc.verified

PVLA

Price:

$93.8

Market Cap:

$1.11B

Palvella Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on developing and commercializing novel therapies to treat patients serious and rare genetic skin diseases. Its lead product candidate is QTORIN 3.9% rapamycin anhydrous gel (QTORIN rapamycin) that is in Phase 3 clinical trial for the treatment of microcystic lymphatic malformations, as well as in Phase 2 clinical trial to treat cutaneous venous malformations. It also develops QTORIN rapamycin for the treatment of other mTOR-driven skin diseases. The company is based in Wayne, Pennsylvania.

Industry

Biotechnology

IPO Date

2015-01-02

Stock Exchange

NASDAQ

Ticker

PVLA

The ROE as of December 2025 (TTM) for Palvella Therapeutics, Inc. (PVLA) is -73.14%

According to Palvella Therapeutics, Inc.’s latest financial reports and current stock price. The company's current ROE is -73.14%. This represents a change of 278.36% compared to the average of -19.33% of the last 4 quarters.

Palvella Therapeutics, Inc. (PVLA) Historical ROE (quarterly & annually)

How has PVLA ROE performed in the past?

The mean historical ROE of Palvella Therapeutics, Inc. over the last ten years is -115.22%. The current -73.14% ROE has changed -36.52% with respect to the historical average. Over the past ten years (40 quarters), PVLA's ROE was at its highest in in the March 2024 quarter at 40.45%. The ROE was at its lowest in in the September 2023 quarter at -35.24%.

Quarterly (TTM)
Annual

Average

-115.22%

Median

-90.12%

Minimum

-481.73%

Maximum

143.60%

Palvella Therapeutics, Inc. (PVLA) ROE by Quarter and Year

Discovering the peaks and valleys of Palvella Therapeutics, Inc. ROE, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 0%

Maximum Annual ROE = 143.60%

Minimum Annual Increase = -435.47%

Minimum Annual ROE = -481.73%

Quarterly (TTM)
Annual
YearROEChange
2024-27.85%-94.22%
2023-481.73%-435.47%
2022143.60%-259.35%
2021-90.12%-24.90%

Palvella Therapeutics, Inc. (PVLA) Average ROE

How has PVLA ROE performed in the past?

The current ROE of Palvella Therapeutics, Inc. (PVLA) is greater than its 3-year, greater than its 5-year, and greater than its 10-year historical averages

3-year avg

-121.99%

5-year avg

-115.22%

10-year avg

-115.22%

Palvella Therapeutics, Inc. (PVLA) ROE vs. Peers

How is PVLA’s ROE compared to its peers?

Palvella Therapeutics, Inc.’s ROE is greater than GH Research PLC (-16.71%), greater than ARS Pharmaceuticals, Inc. (-38.77%), less than Nanobiotix S.A. (155.77%), less than ProKidney Corp. (11.01%), greater than Savara Inc. (-69.05%), greater than Kura Oncology, Inc. (-65.42%), greater than Arbutus Biopharma Corporation (-50.20%), greater than Rezolute, Inc. (-62.82%), greater than EyePoint Pharmaceuticals, Inc. (-76.13%), greater than Tyra Biosciences, Inc. (-31.80%),

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