Olema Pharmaceuticals, Inc.

Olema Pharmaceuticals, Inc.verified

OLMA

Price:

$27.64

Market Cap:

$1.90B

Olema Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company, focuses on the discovery, development, and commercialization of therapies for women's cancers. Its lead product candidate is OP-1250, an estrogen receptor (ER) antagonist and a selective ER degrader, which is in Phase 1/2 clinical trial for the treatment of recurrent, locally advanced, or metastatic estrogen receptor-positive, human epidermal growth factor receptor 2-negative breast cancer. The company was formerly known as CombiThera, Inc. and changed its name to Olema Pharmaceuticals, Inc. in March 2009. Olema Pharmaceuticals, Inc. was incorporated in 2006 and is headquartered in San Francisco, California.

Industry

Biotechnology

IPO Date

2020-11-19

Stock Exchange

NASDAQ

Ticker

OLMA

The ROE as of December 2025 (TTM) for Olema Pharmaceuticals, Inc. (OLMA) is -41.51%

According to Olema Pharmaceuticals, Inc.’s latest financial reports and current stock price. The company's current ROE is -41.51%. This represents a change of 290.24% compared to the average of -10.64% of the last 4 quarters.

Olema Pharmaceuticals, Inc. (OLMA) Historical ROE (quarterly & annually)

How has OLMA ROE performed in the past?

The mean historical ROE of Olema Pharmaceuticals, Inc. over the last ten years is -11.25%. The current -41.51% ROE has changed 268.93% with respect to the historical average. Over the past ten years (40 quarters), OLMA's ROE was at its highest in in the March 2020 quarter at 135.87%. The ROE was at its lowest in in the September 2024 quarter at -17.37%.

Quarterly (TTM)
Annual

Average

-11.25%

Median

-24.98%

Minimum

-53.04%

Maximum

40.74%

Olema Pharmaceuticals, Inc. (OLMA) ROE by Quarter and Year

Discovering the peaks and valleys of Olema Pharmaceuticals, Inc. ROE, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 271.13%

Maximum Annual ROE = 40.74%

Minimum Annual Increase = -116.52%

Minimum Annual ROE = -53.04%

Quarterly (TTM)
Annual
YearROEChange
2024-31.66%-16.84%
2023-38.07%-28.23%
2022-53.04%112.32%
2021-24.98%271.13%
2020-6.73%-116.52%
201940.74%16.42%

Olema Pharmaceuticals, Inc. (OLMA) Average ROE

How has OLMA ROE performed in the past?

The current ROE of Olema Pharmaceuticals, Inc. (OLMA) is greater than its 3-year, greater than its 5-year, and greater than its 10-year historical averages

3-year avg

-40.92%

5-year avg

-30.90%

10-year avg

-11.25%

Olema Pharmaceuticals, Inc. (OLMA) ROE vs. Peers

How is OLMA’s ROE compared to its peers?

Olema Pharmaceuticals, Inc.’s ROE is greater than Ventyx Biosciences, Inc. (-48.11%), greater than Corvus Pharmaceuticals, Inc. (-25.78%), greater than Absci Corporation (-60.21%), greater than REGENXBIO Inc. (-78.29%), greater than Gossamer Bio, Inc. (-1774.72%), greater than Prothena Corporation plc (-72.66%), greater than Verastem, Inc. (-9587.28%), greater than KalVista Pharmaceuticals, Inc. (-195.62%), greater than 4D Molecular Therapeutics, Inc. (-47.27%), greater than Lexicon Pharmaceuticals, Inc. (-83.63%),

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