Cortexyme, Inc.

Cortexyme, Inc.verified

CRTX

Price:

$1.95

Market Cap:

$78.66M

Cortexyme, Inc., a clinical stage biopharmaceutical company, focuses on developing therapeutics for Alzheimer's and other degenerative diseases. Its lead drug candidate is atuzaginstat (COR388), an orally administered brain-penetrating small molecule gingipain inhibitor, which is in Phase II/III clinical trial for use in patients with mild to moderate Alzheimer's disease, as well as for the treatment of oral squamous cell carcinoma, periodontitis, and coronavirus infection. The company was incorporated in 2012 and is headquartered in South San Francisco, California.

Industry

Biotechnology

IPO Date

2019-05-09

Stock Exchange

NASDAQ

Ticker

CRTX

The ROE as of July 2025 (TTM) for Cortexyme, Inc. (CRTX) is -172.68%

According to Cortexyme, Inc.’s latest financial reports and current stock price. The company's current ROE is -172.68%. This represents a change of 257.01% compared to the average of -48.37% of the last 4 quarters.

Cortexyme, Inc. (CRTX) Historical ROE (quarterly & annually)

How has CRTX ROE performed in the past?

The mean historical ROE of Cortexyme, Inc. over the last ten years is -48.21%. The current -172.68% ROE has changed 258.18% with respect to the historical average. Over the past ten years (40 quarters), CRTX's ROE was at its highest in in the March 2018 quarter at 108.87%. The ROE was at its lowest in in the March 2025 quarter at -80.89%.

Quarterly (TTM)
Annual

Average

-48.21%

Median

-40.75%

Minimum

-188.51%

Maximum

60.33%

Cortexyme, Inc. (CRTX) ROE by Quarter and Year

Discovering the peaks and valleys of Cortexyme, Inc. ROE, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 411.04%

Maximum Annual ROE = 60.33%

Minimum Annual Increase = -128.95%

Minimum Annual ROE = -188.51%

Quarterly (TTM)
Annual
YearROEChange
2024-188.51%411.04%
2023-36.89%-28.17%
2022-51.36%-31.82%
2021-75.33%68.85%
2020-44.61%40.02%
2019-31.86%82.39%
2018-17.47%-128.95%

Cortexyme, Inc. (CRTX) Average ROE

How has CRTX ROE performed in the past?

The current ROE of Cortexyme, Inc. (CRTX) is greater than its 3-year, greater than its 5-year, and greater than its 10-year historical averages

3-year avg

-92.25%

5-year avg

-79.34%

10-year avg

-48.21%

Cortexyme, Inc. (CRTX) ROE vs. Peers

How is CRTX’s ROE compared to its peers?

Cortexyme, Inc.’s ROE is

CompanyROEMarket cap

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