The PE Ratio as of December 2025 (TTM) for Lyra Therapeutics, Inc. (LYRA) is -0.20

According to Lyra Therapeutics, Inc.’s latest financial reports and current stock price. The company's current PE Ratio is -0.20. This represents a change of -98.24% compared to the average of -11.39 of the last 4 quarters.

Lyra Therapeutics, Inc. (LYRA) Historical PE Ratio (quarterly & annually)

How has LYRA PE Ratio performed in the past?

The mean historical PE Ratio of Lyra Therapeutics, Inc. over the last ten years is -289.06. The current -0.20 PE Ratio has changed -93.08% with respect to the historical average. Over the past ten years (40 quarters), LYRA's PE Ratio was at its highest in in the June 2025 quarter at -0.41. The PE Ratio was at its lowest in in the March 2020 quarter at -678.48.

Lyra Therapeutics, Inc. (LYRA) PE Ratio by Quarter and Year

Discovering the peaks and valleys of Lyra Therapeutics, Inc. PE Ratio, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Lyra Therapeutics, Inc. (LYRA) Average PE Ratio

How has LYRA PE Ratio performed in the past?

The current PE Ratio of Lyra Therapeutics, Inc. (LYRA) is greater than its 3-year, greater than its 5-year, and greater than its 10-year historical averages

Lyra Therapeutics, Inc. (LYRA) PE Ratio vs. Peers

How is LYRA’s PE Ratio compared to its peers?

Lyra Therapeutics, Inc.’s PE Ratio is less than TransCode Therapeutics, Inc. (-0.00), greater than IN8bio, Inc. (-0.40), greater than Galecto, Inc. (-1.92), greater than Bolt Biotherapeutics, Inc. (-0.24), greater than Cellectar Biosciences, Inc. (-0.21), greater than HCW Biologics Inc. (-0.21), less than Aptevo Therapeutics Inc. (-0.04), greater than AEON Biopharma, Inc. (-2902.68), greater than Cardio Diagnostics Holdings, Inc. (-0.85), less than Cingulate Inc. (-0.00),

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