Lyra Therapeutics, Inc.

Lyra Therapeutics, Inc.verified




Market Cap:


Lyra Therapeutics, Inc., a clinical-stage therapeutics company, focuses on the development and commercialization of novel integrated drug and delivery solutions for the localized treatment of patients with ear, nose, and throat diseases. It's XTreo technology platform is designed to deliver medicines directly to the affected tissue for sustained periods with a single administration. The company's product candidates include LYR-210, an anti-inflammatory implantable drug matrix for the treatment of chronic rhinosinusitis (CRS), which is in Phase II clinical trial; and LYR-220 for CRS patients with and without nasal polyps. The company was formerly known as 480 Biomedical, Inc. and changed its ...[Read more]



IPO Date


Stock Exchange




The PE Ratio as of July 2024 (TTM) for Lyra Therapeutics, Inc. (LYRA) is -0.25

According to Lyra Therapeutics, Inc.’s latest financial reports and current stock price. The company's current PE Ratio is -0.25. This represents a change of -93.68% compared to the average of -3.96 of the last 4 quarters.

Lyra Therapeutics, Inc. (LYRA) Historical PE Ratio (quarterly & annually)

How has LYRA PE Ratio performed in the past?

The mean historical PE Ratio of Lyra Therapeutics, Inc. over the last ten years is -7.64. The current -0.25 PE Ratio has changed 227.12% with respect to the historical average. Over the past ten years (40 quarters), LYRA's PE Ratio was at its highest in in the December 2021 quarter at -1.06. The PE Ratio was at its lowest in in the March 2020 quarter at -13.57.

Quarterly (TTM)









Lyra Therapeutics, Inc. (LYRA) PE Ratio by Quarter and Year

Discovering the peaks and valleys of Lyra Therapeutics, Inc. PE Ratio, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 142.42%

Maximum Annual PE Ratio = -1.34

Minimum Annual Increase = -70.20%

Minimum Annual PE Ratio = -19.29

Quarterly (TTM)
YearPE RatioChange

Lyra Therapeutics, Inc. (LYRA) Average PE Ratio

How has LYRA PE Ratio performed in the past?

The current PE Ratio of Lyra Therapeutics, Inc. (LYRA) is greater than its 3-year, greater than its 5-year, and greater than its 10-year historical averages

3-year avg


5-year avg


10-year avg


Lyra Therapeutics, Inc. (LYRA) PE Ratio vs. Peers

How is LYRA’s PE Ratio compared to its peers?

Lyra Therapeutics, Inc.’s PE Ratio is less than CytomX Therapeutics, Inc. (6.95), greater than Assembly Biosciences, Inc. (-1.59), greater than Achilles Therapeutics plc (-0.50), greater than Neoleukin Therapeutics, Inc. (-0.98), greater than Instil Bio, Inc. (-0.67), greater than NextCure, Inc. (-0.73), less than Spero Therapeutics, Inc. (3.17), greater than Nuvation Bio Inc. (-11.59), greater than Cullinan Oncology, Inc. (-6.69), greater than Bolt Biotherapeutics, Inc. (-0.44), greater than Day One Biopharmaceuticals, Inc. (-6.52), greater than Autolus Therapeutics plc (-4.28),

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