The PE Ratio as of December 2025 (TTM) for Epizyme, Inc. (EPZM) is -0.70

According to Epizyme, Inc.’s latest financial reports and current stock price. The company's current PE Ratio is -0.70. This represents a change of -48.78% compared to the average of -1.38 of the last 4 quarters.

Epizyme, Inc. (EPZM) Historical PE Ratio (quarterly & annually)

How has EPZM PE Ratio performed in the past?

The mean historical PE Ratio of Epizyme, Inc. over the last ten years is -85.47. The current -0.70 PE Ratio has changed -17.59% with respect to the historical average. Over the past ten years (40 quarters), EPZM's PE Ratio was at its highest in in the September 2012 quarter at 28.98. The PE Ratio was at its lowest in in the June 2013 quarter at -30.96.

Epizyme, Inc. (EPZM) PE Ratio by Quarter and Year

Discovering the peaks and valleys of Epizyme, Inc. PE Ratio, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Epizyme, Inc. (EPZM) Average PE Ratio

How has EPZM PE Ratio performed in the past?

The current PE Ratio of Epizyme, Inc. (EPZM) is greater than its 3-year, greater than its 5-year, and greater than its 10-year historical averages

Epizyme, Inc. (EPZM) PE Ratio vs. Peers

How is EPZM’s PE Ratio compared to its peers?

Epizyme, Inc.’s PE Ratio is greater than Acelyrin, Inc. (-0.85), greater than CARGO Therapeutics, Inc. Common Stock (-0.97), greater than Third Harmonic Bio, Inc. (-4.52), greater than Inozyme Pharma, Inc. (-2.41), less than Celularity Inc. (-0.42), less than Catabasis Pharmaceuticals, Inc. (0), greater than Spectrum Pharmaceuticals, Inc. (-2.40), greater than 2seventy bio, Inc. (-64.83), greater than Alaunos Therapeutics, Inc. (-2169.48), greater than Inhibrx Biosciences, Inc. (-8.29),

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