The PE Ratio as of December 2025 (TTM) for Aeglea BioTherapeutics, Inc. (AGLE) is -0.16

According to Aeglea BioTherapeutics, Inc.’s latest financial reports and current stock price. The company's current PE Ratio is -0.16. This represents a change of -99.56% compared to the average of -36.53 of the last 4 quarters.

Aeglea BioTherapeutics, Inc. (AGLE) Historical PE Ratio (quarterly & annually)

How has AGLE PE Ratio performed in the past?

The mean historical PE Ratio of Aeglea BioTherapeutics, Inc. over the last ten years is -3.76. The current -0.16 PE Ratio has changed 330.97% with respect to the historical average. Over the past ten years (40 quarters), AGLE's PE Ratio was at its highest in in the June 2023 quarter at -0.05. The PE Ratio was at its lowest in in the September 2025 quarter at -129.65.

Aeglea BioTherapeutics, Inc. (AGLE) PE Ratio by Quarter and Year

Discovering the peaks and valleys of Aeglea BioTherapeutics, Inc. PE Ratio, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Aeglea BioTherapeutics, Inc. (AGLE) Average PE Ratio

How has AGLE PE Ratio performed in the past?

The current PE Ratio of Aeglea BioTherapeutics, Inc. (AGLE) is greater than its 3-year, greater than its 5-year, and greater than its 10-year historical averages

Aeglea BioTherapeutics, Inc. (AGLE) PE Ratio vs. Peers

How is AGLE’s PE Ratio compared to its peers?

Aeglea BioTherapeutics, Inc.’s PE Ratio is greater than bluebird bio, Inc. (-0.24), greater than GreenLight Biosciences Holdings (-0.24), greater than Lunai Bioworks Inc. (-0.24), greater than AlloVir, Inc. (-3.21), greater than Rein Therapeutics Inc. (-0.69), less than ERYTECH Pharma S.A. (-0.02), greater than Kronos Bio, Inc. (-0.83), less than Magenta Therapeutics, Inc. (-0.02), greater than TCR2 Therapeutics Inc. (-0.38), greater than Pluristem Therapeutics Inc. (-55.09),

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