Aeglea BioTherapeutics, Inc.

Aeglea BioTherapeutics, Inc.verified

AGLE

Price:

$12.01

Market Cap:

$5.04B

Aeglea BioTherapeutics, Inc. is a clinical-stage biotechnology firm dedicated to creating human enzyme therapies for rare metabolic diseases. Their leading candidate, pegzilarginase, a recombinant human Arginase 1, is currently in the pivotal Phase III PEACE trial to assess its safety and effectiveness for treating Arginase 1 deficiency. Furthermore, the company is developing AGLE-177, a polyethylene glycol modified enzyme, which is progressing through Phase I/II clinical trials for homocystinuria. Their early-stage pipeline includes AGLE-325 for cystinuria, along with other ongoing research initiatives. Founded in 2013, the company was initially known as Aeglea BioTherapeutics Holdings, LLC...[Read more]

Industry

Biotechnology

IPO Date

2016-04-07

Stock Exchange

NASDAQ

Ticker

AGLE

The Enterprise Value as of June 2026 (TTM) for Aeglea BioTherapeutics, Inc. (AGLE) is 4.94B

According to Aeglea BioTherapeutics, Inc.’s latest financial reports and current stock price. The company's current Enterprise Value is 4.94B. This represents a change of -35.47% compared to the average of 7.66B of the last 4 quarters.

Aeglea BioTherapeutics, Inc. (AGLE) Historical Enterprise Value (quarterly & annually)

How has AGLE Enterprise Value performed in the past?

The mean historical Enterprise Value of Aeglea BioTherapeutics, Inc. over the last ten years is 1.33B. The current 4.94B Enterprise Value has changed 37.08% with respect to the historical average. Over the past ten years (40 quarters), AGLE's Enterprise Value was at its highest in in the March 2026 quarter at 17.36B. The Enterprise Value was at its lowest in in the June 2023 quarter at -187908015.60.

Quarterly (TTM)
Annual

Average

1.33B

Median

181.70M

Minimum

-40468161.20

Maximum

11.25B

Aeglea BioTherapeutics, Inc. (AGLE) Enterprise Value by Quarter and Year

Discovering the peaks and valleys of Aeglea BioTherapeutics, Inc. Enterprise Value, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 1.02%

Maximum Annual Enterprise Value = 11.25B

Minimum Annual Increase = -2584.37%

Minimum Annual Enterprise Value = -40468161.20

Quarterly (TTM)
Annual
YearEnterprise ValueChange
202511.25B1.02%
20241.01B-2584.37%
2023-40468161.20-626.08%
20227.69M-97.45%
2021302.20M-9.89%
2020335.39M45.88%
2019229.91M72.21%
2018133.50M93.40%
201769.03M-1439.28%
2016-5153996.25-106.26%

Aeglea BioTherapeutics, Inc. (AGLE) Average Enterprise Value

How has AGLE Enterprise Value performed in the past?

The current Enterprise Value of Aeglea BioTherapeutics, Inc. (AGLE) is greater than its 3-year, greater than its 5-year, and greater than its 10-year historical averages

3-year avg

4.07B

5-year avg

2.51B

10-year avg

1.33B

Aeglea BioTherapeutics, Inc. (AGLE) Enterprise Value vs. Peers

How is AGLE’s Enterprise Value compared to its peers?

Aeglea BioTherapeutics, Inc.’s Enterprise Value is greater than bluebird bio, Inc. (158.07M), greater than GreenLight Biosciences Holdings (57.81M), greater than Lunai Bioworks Inc. (11.16M), greater than AlloVir, Inc. (48.71M), greater than Rein Therapeutics Inc. (26.90M), greater than ERYTECH Pharma S.A. (3.80M), greater than Kronos Bio, Inc. (-13835104.00), greater than Magenta Therapeutics, Inc. (-583861976.00), greater than TCR2 Therapeutics Inc. (79.12M), greater than Pluristem Therapeutics Inc. (43.64M),

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