Synlogic, Inc.

Synlogic, Inc.verified

SYBX

Price:

$0.74

Market Cap:

$8.66M

Operating as a clinical-stage biopharmaceutical enterprise, Synlogic, Inc. is dedicated to the creation and progression of synthetic biotic therapeutics aimed at addressing metabolic and immunological conditions across the United States. Its robust portfolio features multiple drug candidates: SYNB1618 and SYNB1934, both non-systemically absorbed and orally administered, are progressing through Phase II clinical trials for phenylketonuria. Another oral, non-systemic agent, SYNB1353, is designed to treat homocystinuria. Furthermore, SYNB8802, an orally taken, non-systemic compound, is currently in Phase I trials for managing enteric hyperoxaluria. Beyond oral treatments, the company is also de...[Read more]

Industry

Biotechnology

IPO Date

2015-09-30

Stock Exchange

NASDAQ

Ticker

SYBX

The ROE as of June 2026 (TTM) for Synlogic, Inc. (SYBX) is -5.42%

According to Synlogic, Inc.’s latest financial reports and current stock price. The company's current ROE is -5.42%. This represents a change of 159.48% compared to the average of -2.09% of the last 4 quarters.

Synlogic, Inc. (SYBX) Historical ROE (quarterly & annually)

How has SYBX ROE performed in the past?

The mean historical ROE of Synlogic, Inc. over the last ten years is -66.13%. The current -5.42% ROE has changed -91.81% with respect to the historical average. Over the past ten years (40 quarters), SYBX's ROE was at its highest in in the June 2024 quarter at 19.26%. The ROE was at its lowest in in the March 2024 quarter at -236.88%.

Quarterly (TTM)
Annual

Average

-66.13%

Median

-45.50%

Minimum

-183.19%

Maximum

-8.47%

Synlogic, Inc. (SYBX) ROE by Quarter and Year

Discovering the peaks and valleys of Synlogic, Inc. ROE, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 94.71%

Maximum Annual ROE = -8.47%

Minimum Annual Increase = -95.38%

Minimum Annual ROE = -183.19%

Quarterly (TTM)
Annual
YearROEChange
2025-8.47%-95.38%
2024-183.19%36.41%
2023-134.29%67.71%
2022-80.07%94.71%
2021-41.12%-19.98%
2020-51.39%56.97%
2019-32.74%-16.11%
2018-39.03%-17.80%
2017-47.48%9.09%
2016-43.52%48.11%

Synlogic, Inc. (SYBX) Average ROE

How has SYBX ROE performed in the past?

The current ROE of Synlogic, Inc. (SYBX) is greater than its 3-year, greater than its 5-year, and greater than its 10-year historical averages

3-year avg

-108.65%

5-year avg

-89.43%

10-year avg

-66.13%

Synlogic, Inc. (SYBX) ROE vs. Peers

How is SYBX’s ROE compared to its peers?

Synlogic, Inc.’s ROE is greater than Lixte Biotechnology Holdings, Inc. (-125.56%), greater than Allarity Therapeutics, Inc. (-109.94%), greater than Lexaria Bioscience Corp. (-190.06%), greater than Cuprina Holdings (Cayman) Limited Class A Ordinary Shares (-1569.05%), greater than Cingulate Inc. (-365.16%), less than Curis, Inc. (805.67%), greater than Entero Therapeutics, Inc. (-18.69%), greater than Kairos Pharma, Ltd. (-92.26%), greater than BriaCell Therapeutics Corp. (-147.92%), greater than Processa Pharmaceuticals, Inc. (-281.30%),

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