Synlogic, Inc.

Synlogic, Inc.verified

SYBX

Price:

$1.15

Market Cap:

$13.45M

Synlogic, Inc., a clinical-stage biopharmaceutical company, engages in the discovery and development of synthetic biotic medicines to treat metabolic and immunological diseases in the United States. Its therapeutic programs include SYNB1618 and SYNB1934 that are orally administered, non-systemically absorbed drug candidates, which are in Phase II clinical trials to treat phenylketonuria; SYNB1353, an orally administered, non-systemically absorbed drug candidate to treat homocystinuria; and SYNB8802, an orally administered, non-systemically absorbed drug candidate that is in Phase I clinical trial for the treatment of enteric hyperoxaluria. The company is also developing SYNB1891, an intratum...[Read more]

Industry

Biotechnology

IPO Date

2015-09-30

Stock Exchange

NASDAQ

Ticker

SYBX

The ROE as of December 2025 (TTM) for Synlogic, Inc. (SYBX) is -26.47%

According to Synlogic, Inc.’s latest financial reports and current stock price. The company's current ROE is -26.47%. This represents a change of 256.94% compared to the average of -7.42% of the last 4 quarters.

Synlogic, Inc. (SYBX) Historical ROE (quarterly & annually)

How has SYBX ROE performed in the past?

The mean historical ROE of Synlogic, Inc. over the last ten years is -67.50%. The current -26.47% ROE has changed -60.78% with respect to the historical average. Over the past ten years (40 quarters), SYBX's ROE was at its highest in in the June 2024 quarter at 12.59%. The ROE was at its lowest in in the March 2024 quarter at -236.88%.

Quarterly (TTM)
Annual

Average

-67.50%

Median

-45.50%

Minimum

-183.19%

Maximum

-29.39%

Synlogic, Inc. (SYBX) ROE by Quarter and Year

Discovering the peaks and valleys of Synlogic, Inc. ROE, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 98.99%

Maximum Annual ROE = -29.39%

Minimum Annual Increase = -188.99%

Minimum Annual ROE = -183.19%

Quarterly (TTM)
Annual
YearROEChange
2024-183.19%36.41%
2023-134.29%71.00%
2022-78.53%98.99%
2021-39.46%-19.63%
2020-49.10%58.30%
2019-31.02%-20.52%
2018-39.03%-17.80%
2017-47.48%9.09%
2016-43.52%48.11%
2015-29.39%-188.99%

Synlogic, Inc. (SYBX) Average ROE

How has SYBX ROE performed in the past?

The current ROE of Synlogic, Inc. (SYBX) is greater than its 3-year, greater than its 5-year, and greater than its 10-year historical averages

3-year avg

-132.01%

5-year avg

-96.92%

10-year avg

-67.50%

Synlogic, Inc. (SYBX) ROE vs. Peers

How is SYBX’s ROE compared to its peers?

Synlogic, Inc.’s ROE is greater than Lixte Biotechnology Holdings, Inc. (-308.56%), greater than Allarity Therapeutics, Inc. (-112.05%), greater than Lexaria Bioscience Corp. (-149.35%), less than Cuprina Holdings (Cayman) Limited Class A Ordinary Shares (42.42%), greater than Cingulate Inc. (-842.45%), less than Curis, Inc. (354.21%), greater than Entero Therapeutics, Inc. (-31.69%), greater than Kairos Pharma, Ltd. (-79.19%), greater than BriaCell Therapeutics Corp. (-439.74%), greater than Processa Pharmaceuticals, Inc. (-342.35%),

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