ProMIS Neurosciences, Inc.

ProMIS Neurosciences, Inc.verified

PMN

Price:

$7.63

Market Cap:

$9.98M

ProMIS Neurosciences, Inc. discovers and develops precision medicine solutions for the treatment of neurodegenerative diseases, primarily Alzheimer's disease (AD), amyotrophic lateral sclerosis (ALS), and multiple system atrophy (MSA) in Canada. The company's proprietary discovery platform comprises ProMIS and Collective Coordinates algorithms to predict novel targets known as disease specific epitopes on the molecular surface of misfolded proteins. Its lead product candidates include PMN310, a monoclonal antibody (mAb) for toxic oligomers in AD; PMN267, a superoxide dismustase 1 and TAR-DNA binding protein 43 in ALS, as well as alpha synuclein in Parkinson's disease and Lewy body dementia; ...[Read more]

Industry

Biotechnology

IPO Date

2007-01-10

Stock Exchange

NASDAQ

Ticker

PMN

The ROE as of December 2025 (TTM) for ProMIS Neurosciences, Inc. (PMN) is -336.93%

According to ProMIS Neurosciences, Inc.’s latest financial reports and current stock price. The company's current ROE is -336.93%. This represents a change of -155.25% compared to the average of 609.84% of the last 4 quarters.

ProMIS Neurosciences, Inc. (PMN) Historical ROE (quarterly & annually)

How has PMN ROE performed in the past?

The mean historical ROE of ProMIS Neurosciences, Inc. over the last ten years is -580.97%. The current -336.93% ROE has changed -42.01% with respect to the historical average. Over the past ten years (40 quarters), PMN's ROE was at its highest in in the June 2025 quarter at 2.64%. The ROE was at its lowest in in the March 2024 quarter at -4714.83%.

Quarterly (TTM)
Annual

Average

-580.97%

Median

-283.48%

Minimum

-3702.09%

Maximum

989.81%

ProMIS Neurosciences, Inc. (PMN) ROE by Quarter and Year

Discovering the peaks and valleys of ProMIS Neurosciences, Inc. ROE, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 1.35%

Maximum Annual ROE = 989.81%

Minimum Annual Increase = -833.56%

Minimum Annual ROE = -3702.09%

Quarterly (TTM)
Annual
YearROEChange
202416.85%-103.61%
2023-466.42%-147.12%
2022989.81%-833.56%
2021-134.93%-124.21%
2020557.37%-130.00%
2019-1857.79%187.77%
2018-645.59%106.78%
2017-312.21%-91.57%
2016-3702.09%1.35%
2015-254.74%-124.77%

ProMIS Neurosciences, Inc. (PMN) Average ROE

How has PMN ROE performed in the past?

The current ROE of ProMIS Neurosciences, Inc. (PMN) is less than than its 3-year, less than than its 5-year, and greater than its 10-year historical averages

3-year avg

180.08%

5-year avg

192.54%

10-year avg

-580.97%

ProMIS Neurosciences, Inc. (PMN) ROE vs. Peers

How is PMN’s ROE compared to its peers?

ProMIS Neurosciences, Inc.’s ROE is less than MapLight Therapeutics, Inc. (0%), greater than Ernexa Therapeutics Inc. (-1949.32%), greater than OSR Holdings, Inc. (-22.68%), greater than Lipocine Inc. (-23.58%), less than Adaptimmune Therapeutics plc (4.10%), greater than Edesa Biotech, Inc. (-69.81%), greater than Adlai Nortye Ltd. (-98.95%), greater than GeoVax Labs, Inc. (-489.66%), greater than Tharimmune, Inc. (-1239.16%), greater than BioRestorative Therapies, Inc. (-145.34%),

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