Lyell Immunopharma, Inc.

Lyell Immunopharma, Inc.verified

LYEL

Price:

$13.5

Market Cap:

$315.01M

Lyell Immunopharma, Inc. (LYEL) is a firm specializing in T cell reprogramming, dedicated to crafting T cell therapies for individuals battling solid tumors. The company's therapeutic innovation relies on advanced technology platforms: Gen-R, an ex vivo genetic reprogramming technique engineered to counteract T cell exhaustion, and Epi-R, an ex vivo epigenetic reprogramming method designed to cultivate T cells with sustained stem-like properties. Its development pipeline features notable candidates such as LYL797, a T cell product aimed at non-small cell lung cancer and triple-negative breast cancers; LYL845, intended for a broad range of solid tumors; and NY-ESO-1, focusing on synovial sarc...[Read more]

Industry

Biotechnology

IPO Date

2021-06-17

Stock Exchange

NASDAQ

Ticker

LYEL

The ROE as of June 2026 (TTM) for Lyell Immunopharma, Inc. (LYEL) is -85.71%

According to Lyell Immunopharma, Inc.’s latest financial reports and current stock price. The company's current ROE is -85.71%. This represents a change of 274.27% compared to the average of -22.90% of the last 4 quarters.

Lyell Immunopharma, Inc. (LYEL) Historical ROE (quarterly & annually)

How has LYEL ROE performed in the past?

The mean historical ROE of Lyell Immunopharma, Inc. over the last ten years is -49.29%. The current -85.71% ROE has changed 73.89% with respect to the historical average. Over the past ten years (40 quarters), LYEL's ROE was at its highest in in the March 2020 quarter at 0%. The ROE was at its lowest in in the December 2025 quarter at -56.70%.

Quarterly (TTM)
Annual

Average

-49.29%

Median

-31.71%

Minimum

-110.57%

Maximum

-21.98%

Lyell Immunopharma, Inc. (LYEL) ROE by Quarter and Year

Discovering the peaks and valleys of Lyell Immunopharma, Inc. ROE, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 150.10%

Maximum Annual ROE = -21.98%

Minimum Annual Increase = -18.34%

Minimum Annual ROE = -110.57%

Quarterly (TTM)
Annual
YearROEChange
2025-110.57%23.41%
2024-89.60%150.10%
2023-35.82%63.01%
2022-21.98%-18.34%
2021-26.91%-5.44%
2020-28.46%-10.24%

Lyell Immunopharma, Inc. (LYEL) Average ROE

How has LYEL ROE performed in the past?

The current ROE of Lyell Immunopharma, Inc. (LYEL) is greater than its 3-year, greater than its 5-year, and greater than its 10-year historical averages

3-year avg

-78.66%

5-year avg

-56.98%

10-year avg

-49.29%

Lyell Immunopharma, Inc. (LYEL) ROE vs. Peers

How is LYEL’s ROE compared to its peers?

Lyell Immunopharma, Inc.’s ROE is greater than AC Immune S.A. (-123.98%), greater than Editas Medicine, Inc. (-677.39%), greater than Allogene Therapeutics, Inc. (-56.45%), greater than Kyverna Therapeutics, Inc. (-81.87%), greater than Silence Therapeutics plc (-121.71%), greater than Larimar Therapeutics, Inc. (-134.14%), greater than Amarin Corporation plc (-7.34%), greater than Cabaletta Bio, Inc. (-131.58%), greater than Aldeyra Therapeutics, Inc. (-57.34%), greater than Genelux Corporation (-165.18%),

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