Gelesis Holdings, Inc.

Gelesis Holdings, Inc.verified

GLS

Price:

$0.1586

Market Cap:

$11.63M

Gelesis Holdings Inc., a commercial stage biotherapeutics company, developing a biomimicry to treat the genesis of obesity and GI-related chronic diseases. The company also provides PLENITY, an orally administered, non-stimulant, and non-systemic aid for weight management. In addition, it offers a product for obesity and overweight and a pipeline with potential therapies for non-alcoholic fatty liver disease/non-alcoholic steatohepatitis, type 2 diabetes, and GS500 for Functional Constipation. Gelesis Holdings Inc. was incorporated in 2006 and is headquartered in Boston, Massachusetts.

Industry

Biotechnology

IPO Date

2022-01-14

Stock Exchange

NYSE

Ticker

GLS

The ROE as of November 2025 (TTM) for Gelesis Holdings, Inc. (GLS) is 31.43%

According to Gelesis Holdings, Inc.’s latest financial reports and current stock price. The company's current ROE is 31.43%. This represents a change of -77.04% compared to the average of 136.89% of the last 4 quarters.

Gelesis Holdings, Inc. (GLS) Historical ROE (quarterly & annually)

How has GLS ROE performed in the past?

The mean historical ROE of Gelesis Holdings, Inc. over the last ten years is 83.64%. The current 31.43% ROE has changed -62.42% with respect to the historical average. Over the past ten years (40 quarters), GLS's ROE was at its highest in in the September 2022 quarter at 393.58%. The ROE was at its lowest in in the June 2021 quarter at -496.70%.

Quarterly (TTM)
Annual

Average

83.64%

Median

28.30%

Minimum

0%

Maximum

222.62%

Gelesis Holdings, Inc. (GLS) ROE by Quarter and Year

Discovering the peaks and valleys of Gelesis Holdings, Inc. ROE, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = Infinity%

Maximum Annual ROE = 222.62%

Minimum Annual Increase = 0%

Minimum Annual ROE = 0%

Quarterly (TTM)
Annual
YearROEChange
2022222.62%686.62%
202128.30%Infinity%

Gelesis Holdings, Inc. (GLS) Average ROE

How has GLS ROE performed in the past?

The current ROE of Gelesis Holdings, Inc. (GLS) is less than than its 3-year, less than than its 5-year, and less than than its 10-year historical averages

3-year avg

83.64%

5-year avg

83.64%

10-year avg

83.64%

Gelesis Holdings, Inc. (GLS) ROE vs. Peers

How is GLS’s ROE compared to its peers?

Gelesis Holdings, Inc.’s ROE is greater than Applied Molecular Transport Inc. (-111.78%), greater than ObsEva S.A. (-146.39%), greater than Korro Bio, Inc. (-61.51%), greater than TuHURA Biosciences, Inc. (-393.18%), greater than Scorpius Holdings, Inc. (-263.90%), greater than Axcella Health Inc. (-620.40%), greater than SQZ Biotechnologies Company (-87.75%), greater than Cyclacel Pharmaceuticals, Inc. (-187.31%), less than Notable Labs, Ltd. (103.08%),

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