Ensysce Biosciences, Inc.

Ensysce Biosciences, Inc. - ROEverified

ENSC

Price:

$0.2713

Market Cap:

$2.52M

Ensysce Biosciences, Inc. is a clinical-stage pharmaceutical firm dedicated to developing novel prescription drugs for the treatment of severe pain in the United States, with a specific focus on preventing opioid addiction, misuse, abuse, and overdose. The company leverages two primary technological frameworks: the Trypsin Activated Abuse Protection (TAAP) platform, which creates opioid prodrugs designed to resist abuse, and the Multi-Pill Abuse Resistance (MPAR) platform, engineered to offer protection against overdose through its advanced opioid prodrug technology. Ensysce's pipeline features several key candidates, including PF614, an oxycodone prodrug developed using the TAAP platform, c...[Read more]

Industry

Biotechnology

IPO Date

2018-03-14

Stock Exchange

NASDAQ

Ticker

ENSC

The ROE as of June 2026 (TTM) for Ensysce Biosciences, Inc. (ENSC) is -631.47%

According to Ensysce Biosciences, Inc.’s latest financial reports and current stock price. The company's current ROE is -631.47%. This represents a change of -521.88% compared to the average of 149.68% of the last 4 quarters.

Ensysce Biosciences, Inc. (ENSC) Historical ROE (quarterly & annually)

How has ENSC ROE performed in the past?

The mean historical ROE of Ensysce Biosciences, Inc. over the last ten years is 436.10%. The current -631.47% ROE has changed -244.80% with respect to the historical average. Over the past ten years (40 quarters), ENSC's ROE was at its highest in in the September 2021 quarter at 16.24%. The ROE was at its lowest in in the March 2023 quarter at -1312.26%.

Quarterly (TTM)
Annual

Average

436.10%

Median

-0.02%

Minimum

-316.63%

Maximum

3.29%

Ensysce Biosciences, Inc. (ENSC) ROE by Quarter and Year

Discovering the peaks and valleys of Ensysce Biosciences, Inc. ROE, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 4.16%

Maximum Annual ROE = 3.29%

Minimum Annual Increase = -41983.36%

Minimum Annual ROE = -316.63%

Quarterly (TTM)
Annual
YearROEChange
2025-316.63%47.02%
2024-215.37%-106.55%
20233.29%405.13%
2022650.76%76.28%
2021369.16%-41983.36%
2020-0.88%-100.58%
2019151.32%-22340.29%
2018-0.68%4.16%

Ensysce Biosciences, Inc. (ENSC) Average ROE

How has ENSC ROE performed in the past?

The current ROE of Ensysce Biosciences, Inc. (ENSC) is less than than its 3-year, less than than its 5-year, and less than than its 10-year historical averages

3-year avg

918.40%

5-year avg

755.03%

10-year avg

436.10%

Ensysce Biosciences, Inc. (ENSC) ROE vs. Peers

How is ENSC’s ROE compared to its peers?

Ensysce Biosciences, Inc.’s ROE is greater than Soligenix, Inc. (-246.04%), less than Titan Pharmaceuticals, Inc. (1.94%), greater than Oragenics, Inc. (-177.32%), greater than KALA BIO, Inc. (-1335.64%), greater than Xenetic Biosciences, Inc. (-39.28%), less than AIM ImmunoTech Inc. (261.84%), greater than VYNE Therapeutics Inc. (-69.57%), greater than Qualigen Therapeutics, Inc. (-94.09%), greater than Kazia Therapeutics Limited (-116.86%), greater than Can-Fite BioPharma Ltd. (-141.01%),

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