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NASDAQ · CAIBiotechnologyUpdated Nov 2, 2026

Caris Life Sciences, Inc. ROE

Profitability, historical returns, and peer comparisons.

The ROE as of November 2026 (TTM) for Caris Life Sciences, Inc. (CAI) is 18.77%

According to Caris Life Sciences, Inc.’s latest financial reports and current stock price. The company's current ROE is 18.77%. This represents a change of 293.27% compared to the average of 4.77% of the last 4 quarters.

Caris Life Sciences, Inc. (CAI) Historical ROE (quarterly & annually)

How has CAI ROE performed in the past?

The mean historical ROE of Caris Life Sciences, Inc. over the last ten years is -0.76%. The current 18.77% ROE has changed -2574.60% with respect to the historical average. Over the past ten years (40 quarters), CAI's ROE was at its highest in in the March 2024 quarter at 564.57%. The ROE was at its lowest in in the June 2025 quarter at -15.85%.

Quarterly (TTM)
Annual

Average

-0.76%

Median

8.52%

Minimum

-93.18%

Maximum

18.85%

Caris Life Sciences, Inc. (CAI) ROE by Quarter and Year

Discovering the peaks and valleys of Caris Life Sciences, Inc. ROE, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 874.98%

Maximum Annual ROE = 18.85%

Minimum Annual Increase = -926.04%

Minimum Annual ROE = -93.18%

Quarterly (TTM)
Annual
YearROEChange
2025-93.18%-926.04%
202411.28%-29.13%
202315.92%-15.55%
202218.85%377.28%
20203.95%-11.72%
20194.47%-60.09%
201811.21%-12.29%
201712.78%874.98%
20161.31%-77.52%
20155.83%-57.24%

Caris Life Sciences, Inc. (CAI) Average ROE

How has CAI ROE performed in the past?

The current ROE of Caris Life Sciences, Inc. (CAI) is greater than its 3-year, greater than its 5-year, and greater than its 10-year historical averages

3-year avg

-22.00%

5-year avg

-8.64%

10-year avg

-0.76%

Caris Life Sciences, Inc. (CAI) ROE vs. Peers

How is CAI’s ROE compared to its peers?

Caris Life Sciences, Inc.’s ROE is greater than Personalis, Inc. (-46.47%), greater than GeneDx Holdings Corp. (-38.72%), greater than NeoGenomics, Inc. (-3.97%), greater than Adaptive Biotechnologies Corporation (-32.64%), greater than Castle Biosciences, Inc. (-4.15%), less than Insight Molecular Diagnostics Inc. (271.76%), greater than bioAffinity Technologies, Inc. (-257.27%),

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