C4X Discovery Holdings plc

C4X Discovery Holdings plcverified

C4XD.L

C4X Discovery Holdings plc operates as a drug discovery company in the United Kingdom. The company provides Taxonomy3, a novel in silico platform technology that utilizes proprietary mathematical algorithms to perform complex multivariate analysis of genetic data; Conformetrix, a technology platform which allows 3D-shapes of free drug molecules to be measured from experimental data, giving medicinal chemists new and unprecedented insights into the behavior and physical properties of drug molecules; and 4Sight for visualizing 4D molecules in virtual reality. The company's product pipeline includes Orexin-1, a receptor antagonist for the treatment of addictive disorders; NRF-2 activator to tre...[Read more]

Industry

Biotechnology

IPO Date

2014-10-23

Stock Exchange

LSE

Ticker

C4XD.L

The ROE as of December 2025 (TTM) for C4X Discovery Holdings plc (C4XD.L) is -121.19%

According to C4X Discovery Holdings plc’s latest financial reports and current stock price. The company's current ROE is -121.19%. This represents a change of 395.36% compared to the average of -24.47% of the last 4 quarters.

C4X Discovery Holdings plc (C4XD.L) Historical ROE (quarterly & annually)

How has C4XD.L ROE performed in the past?

The mean historical ROE of C4X Discovery Holdings plc over the last ten years is -67.82%. The current -121.19% ROE has changed 78.69% with respect to the historical average. Over the past ten years (40 quarters), C4XD.L's ROE was at its highest in in the July 2013 quarter at 99.79%. The ROE was at its lowest in in the July 2023 quarter at -110.72%.

Quarterly (TTM)
Annual

Average

-67.82%

Median

-71.99%

Minimum

-170.10%

Maximum

83.87%

C4X Discovery Holdings plc (C4XD.L) ROE by Quarter and Year

Discovering the peaks and valleys of C4X Discovery Holdings plc ROE, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 1.02%

Maximum Annual ROE = 83.87%

Minimum Annual Increase = -145.85%

Minimum Annual ROE = -170.10%

Quarterly (TTM)
Annual
YearROEChange
2023-170.10%146.06%
2022-69.13%246.83%
2021-19.93%-79.36%
2020-96.57%-37.94%
2019-155.60%1.02%
2018-13.89%-81.45%
2017-74.86%-39.44%
2016-123.60%221.43%
2015-38.45%-145.85%
201483.87%-57.98%

C4X Discovery Holdings plc (C4XD.L) Average ROE

How has C4XD.L ROE performed in the past?

The current ROE of C4X Discovery Holdings plc (C4XD.L) is greater than its 3-year, greater than its 5-year, and greater than its 10-year historical averages

3-year avg

-86.39%

5-year avg

-102.26%

10-year avg

-67.82%

C4X Discovery Holdings plc (C4XD.L) ROE vs. Peers

How is C4XD.L’s ROE compared to its peers?

C4X Discovery Holdings plc’s ROE is greater than Midatech Pharma plc (-63.03%), less than OKYO Pharma Limited (73.68%), greater than Synairgen plc (-51.06%), greater than NetScientific plc (-16.69%), greater than BiVictriX Therapeutics Plc (-67.92%), greater than Theracryf Plc (-44.95%), less than Oncimmune Holdings plc (416.53%), greater than Destiny Pharma plc (-67.28%), greater than Oxford Cannabinoid Technologies Holdings Plc (-86.76%), greater than Redx Pharma Plc (-180.80%),

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