Zynerba Pharmaceuticals, Inc.

Zynerba Pharmaceuticals, Inc.verified

ZYNE

Price:

$1.3

Market Cap:

$70.12M

Zynerba Pharmaceuticals, Inc. operates as a clinical stage specialty pharmaceutical company. The company focuses on developing pharmaceutically-produced transdermal cannabinoid therapies for rare and near-rare neuropsychiatric disorders. It is developing Zygel, a pharmaceutically-produced cannabidiol formulated as a permeation-enhanced gel for transdermal delivery. The company was formerly known as AllTranz, Inc. and changed its name to Zynerba Pharmaceuticals, Inc. in August 2014. Zynerba Pharmaceuticals, Inc. was incorporated in 2007 and is headquartered in Devon, Pennsylvania.

Industry

Drug Manufacturers - Specialty & Generic

IPO Date

2015-08-05

Stock Exchange

NASDAQ

Ticker

ZYNE

The PE Ratio as of November 2025 (TTM) for Zynerba Pharmaceuticals, Inc. (ZYNE) is -1.65

According to Zynerba Pharmaceuticals, Inc.’s latest financial reports and current stock price. The company's current PE Ratio is -1.65. This represents a change of 153.01% compared to the average of -0.65 of the last 4 quarters.

Zynerba Pharmaceuticals, Inc. (ZYNE) Historical PE Ratio (quarterly & annually)

How has ZYNE PE Ratio performed in the past?

The mean historical PE Ratio of Zynerba Pharmaceuticals, Inc. over the last ten years is -18.82. The current -1.65 PE Ratio has changed 774.27% with respect to the historical average. Over the past ten years (40 quarters), ZYNE's PE Ratio was at its highest in in the June 2023 quarter at -0.38. The PE Ratio was at its lowest in in the March 2014 quarter at -96.91.

Quarterly (TTM)
Annual

Average

-18.82

Median

-3.90

Minimum

-146.32

Maximum

-0.65

Zynerba Pharmaceuticals, Inc. (ZYNE) PE Ratio by Quarter and Year

Discovering the peaks and valleys of Zynerba Pharmaceuticals, Inc. PE Ratio, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 271.08%

Maximum Annual PE Ratio = -0.65

Minimum Annual Increase = -88.77%

Minimum Annual PE Ratio = -146.32

Quarterly (TTM)
Annual
YearPE RatioChange
2022-0.65-78.41%
2021-3.0169.97%
2020-1.77-58.15%
2019-4.23271.08%
2018-1.14-77.45%
2017-5.05-16.46%
2016-6.0569.05%
2015-3.58-78.24%
2014-16.43-88.77%

Zynerba Pharmaceuticals, Inc. (ZYNE) Average PE Ratio

How has ZYNE PE Ratio performed in the past?

The current PE Ratio of Zynerba Pharmaceuticals, Inc. (ZYNE) is greater than its 3-year, greater than its 5-year, and greater than its 10-year historical averages

3-year avg

-1.81

5-year avg

-2.16

10-year avg

-18.82

Zynerba Pharmaceuticals, Inc. (ZYNE) PE Ratio vs. Peers

How is ZYNE’s PE Ratio compared to its peers?

Zynerba Pharmaceuticals, Inc.’s PE Ratio is less than The Valens Company Inc. (-0.88), less than Chicago Atlantic BDC, Inc. (10.04), greater than Quince Therapeutics, Inc. (-3.67), greater than DURECT Corporation (-17.05), less than Akoya Biosciences, Inc. (-1.35), less than Zomedica Corp. (-1.12), less than Bonk, Inc. (-0.75), less than IGM Biosciences, Inc. (-1.46), greater than MindWalk Holdings Corp. (-4.37), less than Surface Oncology, Inc. (-0.91),

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