Apellis Pharmaceuticals, Inc.

Apellis Pharmaceuticals, Inc.verified




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Apellis Pharmaceuticals, Inc., a commercial-stage biopharmaceutical company, focuses on the discovery, development, and commercialization of therapeutic compounds through the inhibition of the complement system for autoimmune and inflammatory diseases. The company's lead product candidate is pegcetacoplan that is in Phase III clinical trials for the treatment of geographic atrophy (GA) in age-related macular degeneration and paroxysmal nocturnal hemoglobinuria (PNH) diseases. It also develops EMPAVELI (systemic pegcetacoplan) for the treatment of cold agglutinin disease (CAD), and hematopoietic stem cell transplantation-associated thrombotic microangiopathy (HSCT-TMA) in hematology; C3 glome...[Read more]



IPO Date


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The PE Ratio as of July 2024 (TTM) for Apellis Pharmaceuticals, Inc. (APLS) is -11.51

According to Apellis Pharmaceuticals, Inc.’s latest financial reports and current stock price. The company's current PE Ratio is -11.51. This represents a change of -41.38% compared to the average of -19.63 of the last 4 quarters.

Apellis Pharmaceuticals, Inc. (APLS) Historical PE Ratio (quarterly & annually)

How has APLS PE Ratio performed in the past?

The mean historical PE Ratio of Apellis Pharmaceuticals, Inc. over the last ten years is -9.57. The current -11.51 PE Ratio has changed 11.93% with respect to the historical average. Over the past ten years (40 quarters), APLS's PE Ratio was at its highest in in the December 2020 quarter at 13.86. The PE Ratio was at its lowest in in the March 2024 quarter at -27.63.

Quarterly (TTM)









Apellis Pharmaceuticals, Inc. (APLS) PE Ratio by Quarter and Year

Discovering the peaks and valleys of Apellis Pharmaceuticals, Inc. PE Ratio, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 102.70%

Maximum Annual PE Ratio = -5.35

Minimum Annual Increase = -76.81%

Minimum Annual PE Ratio = -23.53

Quarterly (TTM)
YearPE RatioChange

Apellis Pharmaceuticals, Inc. (APLS) Average PE Ratio

How has APLS PE Ratio performed in the past?

The current PE Ratio of Apellis Pharmaceuticals, Inc. (APLS) is less than than its 3-year, less than than its 5-year, and less than than its 10-year historical averages

3-year avg


5-year avg


10-year avg


Apellis Pharmaceuticals, Inc. (APLS) PE Ratio vs. Peers

How is APLS’s PE Ratio compared to its peers?

Apellis Pharmaceuticals, Inc.’s PE Ratio is greater than Prometheus Biosciences, Inc. (-81.93), less than Akero Therapeutics, Inc. (-8.96), greater than Immunovant, Inc. (-16.80), greater than Madrigal Pharmaceuticals, Inc. (-12.13), less than Day One Biopharmaceuticals, Inc. (-6.49), less than Mirati Therapeutics, Inc. (-5.32), less than Amylyx Pharmaceuticals, Inc. (-2.02), less than Terns Pharmaceuticals, Inc. (-7.88), less than X4 Pharmaceuticals, Inc. (-1.15), less than Inozyme Pharma, Inc. (-4.60), greater than Mereo BioPharma Group plc (-77.48), greater than Blueprint Medicines Corporation (-24.43), greater than Cerevel Therapeutics Holdings, Inc. (-16.85), less than Acumen Pharmaceuticals, Inc. (-3.28),

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