NuCana plc

NuCana plcverified

NCNA

Price:

$4.43

Market Cap:

$20.16M

NuCana plc, a clinical-stage biopharmaceutical company, engages in the development of products for the treatment of cancer. The company develops its products based on its proprietary ProTide technology. Its lead product candidate includes Acelarin, which is in Phase I clinical trial for patients with advanced solid tumors; Phase Ib for patients with recurrent ovarian cancer; Phase Ib clinical trials for the treatment of patients with biliary tract cancer; Phase II clinical trial for the treatment of patients with platinum-resistant ovarian cancer; and Phase III clinical trial for the treatment of patients with pancreatic cancer. The company is also developing NUC-3373, a ProTide transformati...[Read more]

Industry

Biotechnology

IPO Date

2017-09-28

Stock Exchange

NASDAQ

Ticker

NCNA

The ROE as of December 2025 (TTM) for NuCana plc (NCNA) is -580.99%

According to NuCana plc’s latest financial reports and current stock price. The company's current ROE is -580.99%. This represents a change of 364.29% compared to the average of -125.13% of the last 4 quarters.

NuCana plc (NCNA) Historical ROE (quarterly & annually)

How has NCNA ROE performed in the past?

The mean historical ROE of NuCana plc over the last ten years is -79.77%. The current -580.99% ROE has changed 628.29% with respect to the historical average. Over the past ten years (40 quarters), NCNA's ROE was at its highest in in the June 2016 quarter at 0%. The ROE was at its lowest in in the March 2017 quarter at -6485.48%.

Quarterly (TTM)
Annual

Average

-79.77%

Median

-32.31%

Minimum

-319.06%

Maximum

-16.96%

NuCana plc (NCNA) ROE by Quarter and Year

Discovering the peaks and valleys of NuCana plc ROE, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 123.18%

Maximum Annual ROE = -16.96%

Minimum Annual Increase = -31.36%

Minimum Annual ROE = -319.06%

Quarterly (TTM)
Annual
YearROEChange
2024-319.06%71.90%
2023-185.61%123.18%
2022-83.17%34.49%
2021-61.84%99.99%
2020-30.92%-8.27%
2019-33.71%98.73%
2018-16.96%-31.36%
2017-24.71%3.11%
2016-23.96%34.66%
2015-17.80%-0.52%

NuCana plc (NCNA) Average ROE

How has NCNA ROE performed in the past?

The current ROE of NuCana plc (NCNA) is greater than its 3-year, greater than its 5-year, and greater than its 10-year historical averages

3-year avg

-195.95%

5-year avg

-136.12%

10-year avg

-79.77%

NuCana plc (NCNA) ROE vs. Peers

How is NCNA’s ROE compared to its peers?

NuCana plc’s ROE is greater than MetaVia Inc. (-212.00%), greater than Lisata Therapeutics, Inc. (-78.18%), greater than Passage Bio, Inc. (-103.87%), greater than Enlivex Therapeutics Ltd. (-62.91%), greater than CytoMed Therapeutics Limited (-54.74%), less than CASI Pharmaceuticals, Inc. (358.32%), greater than Pelthos Therapeutics Inc. (-210.32%), greater than CollPlant Biotechnologies Ltd. (-102.03%), less than NeuroSense Therapeutics Ltd. (2.72%), less than Clearside Biomedical, Inc. (65.87%),

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