CRISM Therapeutics Corporation

CRISM Therapeutics Corporationverified

CRTX.L

CRISM Therapeutics Corporation focuses on drug delivery technology to improve the clinical performance of cancer drugs as treatments for solid tumors. Its lead product, ChemoSeed that can be implanted directly into a tumor or the resection margin following the removal of a tumor, ensuring effective therapeutic concentrations of chemotherapy drugs directly reach the tumor tissue. Its ChemoSeed used for treatment of gliomas, a brain tumor. The company was founded in 2016 and is based in Road Town, the British Virgin Islands.

Industry

Biotechnology

IPO Date

2003-10-17

Stock Exchange

LSE

Ticker

CRTX.L

The ROE as of December 2025 (TTM) for CRISM Therapeutics Corporation (CRTX.L) is -79.01%

According to CRISM Therapeutics Corporation’s latest financial reports and current stock price. The company's current ROE is -79.01%. This represents a change of 286.08% compared to the average of -20.46% of the last 4 quarters.

CRISM Therapeutics Corporation (CRTX.L) Historical ROE (quarterly & annually)

How has CRTX.L ROE performed in the past?

The mean historical ROE of CRISM Therapeutics Corporation over the last ten years is -38.28%. The current -79.01% ROE has changed 106.40% with respect to the historical average. Over the past ten years (40 quarters), CRTX.L's ROE was at its highest in in the June 2021 quarter at 0.73%. The ROE was at its lowest in in the June 2025 quarter at -70.99%.

Quarterly (TTM)
Annual

Average

-38.28%

Median

-10.58%

Minimum

-233.92%

Maximum

-4.27%

CRISM Therapeutics Corporation (CRTX.L) ROE by Quarter and Year

Discovering the peaks and valleys of CRISM Therapeutics Corporation ROE, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 2.11%

Maximum Annual ROE = -4.27%

Minimum Annual Increase = -82.41%

Minimum Annual ROE = -233.92%

Quarterly (TTM)
Annual
YearROEChange
2024-41.15%-82.41%
2023-233.92%2.11%
2022-10.58%106.50%
2021-5.12%-22.82%
2020-6.64%-25.53%
2019-8.91%-33.38%
2018-13.38%213.21%
2017-4.27%-79.19%

CRISM Therapeutics Corporation (CRTX.L) Average ROE

How has CRTX.L ROE performed in the past?

The current ROE of CRISM Therapeutics Corporation (CRTX.L) is greater than its 3-year, greater than its 5-year, and greater than its 10-year historical averages

3-year avg

-95.22%

5-year avg

-59.48%

10-year avg

-38.28%

CRISM Therapeutics Corporation (CRTX.L) ROE vs. Peers

How is CRTX.L’s ROE compared to its peers?

CRISM Therapeutics Corporation’s ROE is greater than Tissue Regenix Group plc (-2.38%), greater than Theracryf Plc (-44.95%), greater than MyHealthChecked PLC (-30.82%), less than Proteome Sciences plc (44.15%), greater than N4 Pharma Plc (-91.34%), greater than Oxford BioDynamics Plc (-244.86%), less than Cizzle Biotechnology Holdings Plc (-0.49%), greater than Roquefort Therapeutics plc (-19.80%), less than Chill Brands Group PLC (897.79%), greater than Feedback plc (-83.25%),

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